Pharmacokinetics and tolerance of DU-6859a, a new fluoroquinolone, after single and multiple oral doses in healthy volunteers.

The pharmacokinetics and tolerance of DU-6859a, 7-[(7S)-7-amino-5-azaspiro[2,4]heptan-5-yl]-8-chloro-6-fluor o-1-[(1R, 2S)-2-fluoro-1-cyclopropyl]-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid sesquihydrate, were investigated in healthy male Japanese volunteers after single (25, 50, 100, and 200 mg)...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Nakashima, M, Uematsu, T, Kosuge, K, Umemura, K, Hakusui, H, Tanaka, M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162504/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7695301/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.1.170
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