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The Mengovirus Leader Protein Suppresses Alpha/Beta Interferon Production by Inhibition of the Iron/Ferritin-Mediated Activation of NF-κB

In our studies on the biological function of the mengovirus leader protein, we identified a casein kinase II (CK-2) phosphorylation site in the protein. Here we report that the mengovirus leader protein can be phosphorylated by CK-2 in vitro. Expression of a recombinant leader protein in which the c...

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Udgivet i:J Virol
Principais autores: Zoll, Jan, Melchers, Willem J. G., Galama, Jochem M. D., van Kuppeveld, Frank J. M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2002
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136484/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12208945/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.19.9664-9672.2002
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