The Mengovirus Leader Protein Suppresses Alpha/Beta Interferon Production by Inhibition of the Iron/Ferritin-Mediated Activation of NF-κB

In our studies on the biological function of the mengovirus leader protein, we identified a casein kinase II (CK-2) phosphorylation site in the protein. Here we report that the mengovirus leader protein can be phosphorylated by CK-2 in vitro. Expression of a recombinant leader protein in which the c...

Full description

Saved in:
Bibliographic Details
Main Authors: Zoll, Jan, Melchers, Willem J. G., Galama, Jochem M. D., van Kuppeveld, Frank J. M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC136484/
https://ncbi.nlm.nih.gov/pubmed/12208945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.19.9664-9672.2002
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items