Coxsackie B3 virus protein 2B contains cationic amphipathic helix that is required for viral RNA replication.

Enterovirus protein 2B has been shown to increase plasma membrane permeability. We have identified a conserved putative amphipathic alpha-helix with a narrow hydrophilic face and an arrangement of cationic residues that is typical for the so-called lytic polypeptides. To examine the functional and s...

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Bibliographic Details
Main Authors: van Kuppeveld, F J, Galama, J M, Zoll, J, van den Hurk, P J, Melchers, W J
Format: Artigo
Language:Inglês
Published: 1996
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC190265/
https://ncbi.nlm.nih.gov/pubmed/8648724
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