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Coxsackie B3 virus protein 2B contains cationic amphipathic helix that is required for viral RNA replication.

Enterovirus protein 2B has been shown to increase plasma membrane permeability. We have identified a conserved putative amphipathic alpha-helix with a narrow hydrophilic face and an arrangement of cationic residues that is typical for the so-called lytic polypeptides. To examine the functional and s...

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Udgivet i:J Virol
Principais autores: van Kuppeveld, F J, Galama, J M, Zoll, J, van den Hurk, P J, Melchers, W J
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190265/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8648724/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.6.3876-3886.1996
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