Mutational analysis of the mengovirus poly(C) tract and surrounding heteropolymeric sequences.

Previously, we described three mengovirus mutants derived from cDNA plasmids, containing shortened poly(C) tracts (C8, C12, and C13UC10), that exhibited strong attenuation for virulence in mice yet grew like wild-type virus in HeLa cells. Thirteen additional mutants hav now been constructed and char...

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Detaylı Bibliyografya
Asıl Yazarlar: Martin, L R, Duke, G M, Osorio, J E, Hall, D J, Palmenberg, A C
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1996
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC190034/
https://ncbi.nlm.nih.gov/pubmed/8627731
Etiketler: Etiketle
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