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Mutational analysis of the mengovirus poly(C) tract and surrounding heteropolymeric sequences.

Previously, we described three mengovirus mutants derived from cDNA plasmids, containing shortened poly(C) tracts (C8, C12, and C13UC10), that exhibited strong attenuation for virulence in mice yet grew like wild-type virus in HeLa cells. Thirteen additional mutants hav now been constructed and char...

詳細記述

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書誌詳細
主要な著者: Martin, L R, Duke, G M, Osorio, J E, Hall, D J, Palmenberg, A C
フォーマット: Artigo
言語:Inglês
出版事項: 1996
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC190034/
https://ncbi.nlm.nih.gov/pubmed/8627731
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