Mutational analysis of the mengovirus poly(C) tract and surrounding heteropolymeric sequences.

Previously, we described three mengovirus mutants derived from cDNA plasmids, containing shortened poly(C) tracts (C8, C12, and C13UC10), that exhibited strong attenuation for virulence in mice yet grew like wild-type virus in HeLa cells. Thirteen additional mutants hav now been constructed and char...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Martin, L R, Duke, G M, Osorio, J E, Hall, D J, Palmenberg, A C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190034/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8627731/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.3.2027-2031.1996
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