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Identification of human liver cytochrome P450 isoforms mediating omeprazole metabolism.

1 The in vitro metabolism of omeprazole was studied in human liver microsomes in order to define the metabolic pathways and identify the cytochrome P450 (CYP) isoforms responsible for the formation of the major omeprazole metabolites. 2 The four major metabolites identified in vitro, in tentative or...

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Détails bibliographiques
Auteurs principaux: Andersson, T, Miners, J O, Veronese, M E, Tassaneeyakul, W, Meyer, U A, Birkett, D J
Format: Artigo
Langue:Inglês
Publié: 1993
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1364656/
https://ncbi.nlm.nih.gov/pubmed/12959268
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