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Identification of human liver cytochrome P450 isoforms mediating omeprazole metabolism.

1 The in vitro metabolism of omeprazole was studied in human liver microsomes in order to define the metabolic pathways and identify the cytochrome P450 (CYP) isoforms responsible for the formation of the major omeprazole metabolites. 2 The four major metabolites identified in vitro, in tentative or...

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Autors principals: Andersson, T, Miners, J O, Veronese, M E, Tassaneeyakul, W, Meyer, U A, Birkett, D J
Format: Artigo
Idioma:Inglês
Publicat: 1993
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1364656/
https://ncbi.nlm.nih.gov/pubmed/12959268
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