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Nucleoside Analog Resistance Caused by Insertions in the Fingers of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Involves ATP-Mediated Excision

Although anti-human immunodeficiency virus type 1 (HIV-1) therapy has prolonged the lives of patients, drug resistance is a significant problem. Of particular concern are mutations that cause cross-resistance to a particular class of drugs. Among the mutations that cause resistance to several nucleo...

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Detalhes bibliográficos
Main Authors: Boyer, Paul L., Sarafianos, Stefan G., Arnold, Edward, Hughes, Stephen H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136461/
https://ncbi.nlm.nih.gov/pubmed/12186898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.18.9143-9151.2002
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