Effects of Human Immunodeficiency Virus Type 1 Resistance to Protease Inhibitors on Reverse Transcriptase Processing, Activity, and Drug Sensitivity

Human immunodeficiency virus type 1 (HIV-1) variants resistant to protease inhibitors often display a reduced replicative capacity as a result of an impairment of protease function. Such fitness-impaired viruses display Gag precursor maturation defects. Here, we report that some protease inhibitor-r...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	de la Carrière, Laurence Carron, Paulous, Sylvie, Clavel, François, Mammano, Fabrizio
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Vaccines and Antiviral Agents
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104112/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10074202/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.4.3455-3459.1999
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