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Signals That Dictate Nuclear, Nucleolar, and Cytoplasmic Shuttling of the γ(1)34.5 Protein of Herpes Simplex Virus Type 1
The γ(1)34.5 protein of herpes simplex virus type 1 (HSV-1) is required for viral neurovirulence in vivo. In infected cells, this viral protein prevents the shutoff of protein synthesis mediated by double-stranded-RNA-dependent protein kinase PKR. This is accomplished by recruiting protein phosphata...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC136443/ https://ncbi.nlm.nih.gov/pubmed/12186925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.18.9434-9445.2002 |
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