A Single Amino Acid Mutation in the PA Subunit of the Influenza Virus RNA Polymerase Inhibits Endonucleolytic Cleavage of Capped RNAs

The influenza A virus RNA-dependent RNA polymerase consists of three subunits—PB1, PB2, and PA. The PB1 subunit is the catalytically active polymerase, catalyzing the sequential addition of nucleotides to the growing RNA chain. The PB2 subunit is a cap-binding protein that plays a role in initiation...

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Bibliografski detalji

Izdano u:	J Virol
Glavni autori:	Fodor, Ervin, Crow, Mandy, Mingay, Louise J., Deng, Tao, Sharps, Jane, Fechter, Pierre, Brownlee, George G.
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2002
Teme:	Replication
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136441/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12186883/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.18.8989-9001.2002
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