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Polyuridylated mRNA Synthesized by a Recombinant Influenza Virus Is Defective in Nuclear Export

The poly(A) tail of influenza virus mRNA is synthesized by reiterative copying of a U track near the 5′ end of the virion RNA (vRNA) template by the viral RNA polymerase. We have engineered a novel influenza A/WSN/33 virus which contains a neuraminidase (NA) vRNA with its U track mutated into an A t...

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Bibliografiske detaljer
Main Authors: Poon, Leo L. M., Fodor, Ervin, Brownlee, George G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC111553/
https://ncbi.nlm.nih.gov/pubmed/10590131
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