Combination of Drugs and Drug-Resistant Reverse Transcriptase Results in a Multiplicative Increase of Human Immunodeficiency Virus Type 1 Mutant Frequencies

Replication of drug-resistant human immunodeficiency virus type 1 (HIV-1) in the presence of drug can lead to the failure of antiretroviral drug treatment. Drug failure is associated with the accumulation of drug resistance mutations. Previous studies have shown that 3′-azido-3′-deoxythymidine (AZT)...

Полное описание

Библиографические подробности

Опубликовано в::	J Virol
Главные авторы:	Mansky, Louis M., Pearl, Dennis K., Gajary, Lisa C.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 2002
Предметы:	Vaccines and Antiviral Agents
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136424/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12186909/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.18.9253-9259.2002
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!