Combination of Drugs and Drug-Resistant Reverse Transcriptase Results in a Multiplicative Increase of Human Immunodeficiency Virus Type 1 Mutant Frequencies

Replication of drug-resistant human immunodeficiency virus type 1 (HIV-1) in the presence of drug can lead to the failure of antiretroviral drug treatment. Drug failure is associated with the accumulation of drug resistance mutations. Previous studies have shown that 3′-azido-3′-deoxythymidine (AZT)...

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Vydáno v:	J Virol
Hlavní autoři:	Mansky, Louis M., Pearl, Dennis K., Gajary, Lisa C.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2002
Témata:	Vaccines and Antiviral Agents
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136424/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12186909/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.18.9253-9259.2002
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