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Elimination of T-cell-receptor beta-chain diversity in transgenic mice restricts antigen-specific but not alloreactive responses.

The contribution of T-cell-receptor beta-chain diversity to the T-cell antigen-specific repertoire was investigated using single-chain T-cell-receptor transgenic mice. Animals that express the rearranged beta-chain gene from a T hybridoma with specificity for a hen egg lysozyme peptide, designated H...

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Detaylı Bibliyografya
Asıl Yazarlar: O'Brien, D P, Baecher-Allan, C M, Burns, R P, Shastri, N, Barth, R K
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1997
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1364006/
https://ncbi.nlm.nih.gov/pubmed/9301526
Etiketler: Etiketle
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