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Elimination of T-cell-receptor beta-chain diversity in transgenic mice restricts antigen-specific but not alloreactive responses.
The contribution of T-cell-receptor beta-chain diversity to the T-cell antigen-specific repertoire was investigated using single-chain T-cell-receptor transgenic mice. Animals that express the rearranged beta-chain gene from a T hybridoma with specificity for a hen egg lysozyme peptide, designated H...
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Главные авторы: | , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
1997
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1364006/ https://ncbi.nlm.nih.gov/pubmed/9301526 |
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