Robust Recall and Long-Term Memory T-Cell Responses Induced by Prime-Boost Regimens with Heterologous Live Viral Vectors Expressing Human Immunodeficiency Virus Type 1 Gag and Env Proteins

We investigated long-term memory and recall cellular immune responses to human immunodeficiency virus type 1 (HIV-1) Env and Gag proteins elicited by recombinant vesicular stomatitis viruses (VSVs) expressing Env and Gag. More than 7 months after a single vaccination with VSV-Env, ∼6% of CD8(+) sple...

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Main Authors: Haglund, Karl, Leiner, Ingrid, Kerksiek, Kristen, Buonocore, Linda, Pamer, Eric, Rose, John K.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC136360/
https://ncbi.nlm.nih.gov/pubmed/12097563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.15.7506-7517.2002
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