Preferential Targeting of Conserved Gag Regions after Vaccination with a Heterologous DNA Prime-Modified Vaccinia Virus Ankara Boost HIV-1 Vaccine Regimen

Prime-boost vaccination strategies against HIV-1 often include multiple variants for a given immunogen for better coverage of the extensive viral diversity. To study the immunologic effects of this approach, we characterized breadth, phenotype, function, and specificity of Gag-specific T cells induc...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Bauer, Asli, Podola, Lilli, Mann, Philipp, Missanga, Marco, Haule, Antelmo, Sudi, Lwitiho, Nilsson, Charlotta, Kaluwa, Bahati, Lueer, Cornelia, Mwakatima, Maria, Munseri, Patricia J., Maboko, Leonard, Robb, Merlin L., Tovanabutra, Sodsai, Kijak, Gustavo, Marovich, Mary, McCormack, Sheena, Joseph, Sarah, Lyamuya, Eligius, Wahren, Britta, Sandström, Eric, Biberfeld, Gunnel, Hoelscher, Michael, Bakari, Muhammad, Kroidl, Arne, Geldmacher, Christof
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2017
Teme:
Vaccines and Antiviral Agents
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571275/
https://ncbi.nlm.nih.gov/pubmed/28701395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00730-17
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