Preferential Targeting of Conserved Gag Regions after Vaccination with a Heterologous DNA Prime-Modified Vaccinia Virus Ankara Boost HIV-1 Vaccine Regimen

Prime-boost vaccination strategies against HIV-1 often include multiple variants for a given immunogen for better coverage of the extensive viral diversity. To study the immunologic effects of this approach, we characterized breadth, phenotype, function, and specificity of Gag-specific T cells induc...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Bauer, Asli, Podola, Lilli, Mann, Philipp, Missanga, Marco, Haule, Antelmo, Sudi, Lwitiho, Nilsson, Charlotta, Kaluwa, Bahati, Lueer, Cornelia, Mwakatima, Maria, Munseri, Patricia J., Maboko, Leonard, Robb, Merlin L., Tovanabutra, Sodsai, Kijak, Gustavo, Marovich, Mary, McCormack, Sheena, Joseph, Sarah, Lyamuya, Eligius, Wahren, Britta, Sandström, Eric, Biberfeld, Gunnel, Hoelscher, Michael, Bakari, Muhammad, Kroidl, Arne, Geldmacher, Christof
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571275/
https://ncbi.nlm.nih.gov/pubmed/28701395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00730-17
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