Preferential Targeting of Conserved Gag Regions after Vaccination with a Heterologous DNA Prime-Modified Vaccinia Virus Ankara Boost HIV-1 Vaccine Regimen

Prime-boost vaccination strategies against HIV-1 often include multiple variants for a given immunogen for better coverage of the extensive viral diversity. To study the immunologic effects of this approach, we characterized breadth, phenotype, function, and specificity of Gag-specific T cells induc...

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Библиографические подробности
Опубликовано в: :J Virol
Главные авторы: Bauer, Asli, Podola, Lilli, Mann, Philipp, Missanga, Marco, Haule, Antelmo, Sudi, Lwitiho, Nilsson, Charlotta, Kaluwa, Bahati, Lueer, Cornelia, Mwakatima, Maria, Munseri, Patricia J., Maboko, Leonard, Robb, Merlin L., Tovanabutra, Sodsai, Kijak, Gustavo, Marovich, Mary, McCormack, Sheena, Joseph, Sarah, Lyamuya, Eligius, Wahren, Britta, Sandström, Eric, Biberfeld, Gunnel, Hoelscher, Michael, Bakari, Muhammad, Kroidl, Arne, Geldmacher, Christof
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2017
Предметы:
Vaccines and Antiviral Agents
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571275/
https://ncbi.nlm.nih.gov/pubmed/28701395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00730-17
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