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Enhanced Breadth of CD4 T-Cell Immunity by DNA Prime and Adenovirus Boost Immunization to Human Immunodeficiency Virus Env and Gag Immunogens

A variety of gene-based vaccination approaches have been used to enhance the immune response to viral pathogens. Among them, the ability to perform heterologous immunization by priming with DNA and boosting with replication-defective adenoviral (ADV) vectors encoding foreign antigens has proven part...

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Detalhes bibliográficos
Main Authors: Wu, Lan, Kong, Wing-pui, Nabel, Gary J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1143709/
https://ncbi.nlm.nih.gov/pubmed/15956548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.13.8024-8031.2005
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