Modifications of the Human Immunodeficiency Virus Envelope Glycoprotein Enhance Immunogenicity for Genetic Immunization

In this study, we have investigated the effect of specific mutations in human immunodeficiency virus type 1 (HIV-1) envelope (Env) on antibody production in an effort to improve humoral immune responses to this glycoprotein by DNA vaccination. Mice were injected with plasmid expression vectors encod...

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Detalhes bibliográficos
Main Authors: Chakrabarti, Bimal K., Kong, Wing-pui, Wu, Bei-yue, Yang, Zhi-Yong, Friborg, Jacques, Ling, Xu, King, Steven R., Montefiori, David C., Nabel, Gary J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC137015/
https://ncbi.nlm.nih.gov/pubmed/11991964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.11.5357-5368.2002
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