Overcoming Immunity to a Viral Vaccine by DNA Priming before Vector Boosting

Replication-defective adenovirus (ADV) and poxvirus vectors have shown potential as vaccines for pathogens such as Ebola or human immunodeficiency virus in nonhuman primates, but prior immunity to the viral vector in humans may limit their clinical efficacy. To overcome this limitation, the effect o...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Yang, Zhi-yong, Wyatt, Linda S., Kong, Wing-pui, Moodie, Zoe, Moss, Bernard, Nabel, Gary J.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2003
Fag:	Vaccines and Antiviral Agents
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140625/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12477888/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.1.799-803.2003
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