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Overcoming Immunity to a Viral Vaccine by DNA Priming before Vector Boosting
Replication-defective adenovirus (ADV) and poxvirus vectors have shown potential as vaccines for pathogens such as Ebola or human immunodeficiency virus in nonhuman primates, but prior immunity to the viral vector in humans may limit their clinical efficacy. To overcome this limitation, the effect o...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Microbiology
2003
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC140625/ https://ncbi.nlm.nih.gov/pubmed/12477888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.1.799-803.2003 |
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