A Single Mutation in the E2 Glycoprotein Important for Neurovirulence Influences Binding of Sindbis Virus to Neuroblastoma Cells

The amino acid at position 55 of the E2 glycoprotein (E2(55)) of Sindbis virus (SV) is a critical determinant of SV neurovirulence in mice. Recombinant virus strain TE (E2(55) = histidine) differs only at this position from virus strain 633 (E2(55)= glutamine), yet TE is considerably more neurovirul...

Descripció completa

Dades bibliogràfiques

Publicat a:	J Virol
Autors principals:	Lee, Peiyu, Knight, Ronald, Smit, Jolanda M., Wilschut, Jan, Griffin, Diane E.
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2002
Matèries:	Virus-Cell Interactions
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136218/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12021363/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.12.6302-6310.2002
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!