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Novel Mutations That Control the Sphingolipid and Cholesterol Dependence of the Semliki Forest Virus Fusion Protein

The enveloped alphavirus Semliki Forest virus (SFV) infects cells via a membrane fusion reaction mediated by the E1 membrane protein. Efficient SFV-membrane fusion requires the presence of cholesterol and sphingolipid in the target membrane. Here we report on two mutants, srf-4 and srf-5, selected f...

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Bibliografiset tiedot
Päätekijät: Chatterjee, Prodyot K., Eng, Christina H., Kielian, Margaret
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2002
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC136714/
https://ncbi.nlm.nih.gov/pubmed/12438597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.24.12712-12722.2002
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