Novel Mutations That Control the Sphingolipid and Cholesterol Dependence of the Semliki Forest Virus Fusion Protein

The enveloped alphavirus Semliki Forest virus (SFV) infects cells via a membrane fusion reaction mediated by the E1 membrane protein. Efficient SFV-membrane fusion requires the presence of cholesterol and sphingolipid in the target membrane. Here we report on two mutants, srf-4 and srf-5, selected f...

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Pubblicato in:	J Virol
Autori principali:	Chatterjee, Prodyot K., Eng, Christina H., Kielian, Margaret
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2002
Soggetti:	Virus-Cell Interactions
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136714/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12438597/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.24.12712-12722.2002
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