تحميل...

Binding of a novel SMG-1–Upf1–eRF1–eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay

Nonsense-mediated mRNA decay (NMD) is a surveillance mechanism that degrades mRNA containing premature termination codons (PTCs). In mammalian cells, recognition of PTCs requires translation and depends on the presence on the mRNA with the splicing-dependent exon junction complex (EJC). While it is...

وصف كامل

محفوظ في:

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Kashima, Isao, Yamashita, Akio, Izumi, Natsuko, Kataoka, Naoyuki, Morishita, Ryo, Hoshino, Shinichi, Ohno, Mutsuhito, Dreyfuss, Gideon, Ohno, Shigeo
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Cold Spring Harbor Laboratory Press 2006
الموضوعات:	Research Papers
الوصول للمادة أونلاين:	https://ncbi.nlm.nih.gov/pmc/articles/PMC1361706/ https://ncbi.nlm.nih.gov/pubmed/16452507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1389006
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

Binding of a novel SMG-1–Upf1–eRF1–eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay

مواد مشابهة