Human nonsense-mediated mRNA decay factor UPF2 interacts directly with eRF3 and the SURF complex

Nonsense-mediated mRNA decay (NMD) is an mRNA degradation pathway that regulates gene expression and mRNA quality. A complex network of macromolecular interactions regulates NMD initiation, which is only partially understood. According to prevailing models, NMD begins by the assembly of the SURF (SM...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: López-Perrote, Andrés, Castaño, Raquel, Melero, Roberto, Zamarro, Teresa, Kurosawa, Hitomi, Ohnishi, Tetsuo, Uchiyama, Akiko, Aoyagi, Kyoko, Buchwald, Gretel, Kataoka, Naoyuki, Yamashita, Akio, Llorca, Oscar
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2016
Onderwerpen:
RNA
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770235/
https://ncbi.nlm.nih.gov/pubmed/26740584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1527
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