GTP-dependent structural rearrangement of the eRF1:eRF3 complex and eRF3 sequence motifs essential for PABP binding

Translation termination in eukaryotes is governed by the concerted action of eRF1 and eRF3 factors. eRF1 recognizes the stop codon in the A site of the ribosome and promotes nascent peptide chain release, and the GTPase eRF3 facilitates this peptide release via its interaction with eRF1. In addition...

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Autors principals: Kononenko, Artem V., Mitkevich, Vladimir A., Atkinson, Gemma C., Tenson, Tanel, Dubovaya, Vera I., Frolova, Ludmila Yu, Makarov, Alexander A., Hauryliuk, Vasili
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
Matèries:
Molecular Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811017/
https://ncbi.nlm.nih.gov/pubmed/19906736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp908
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