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Expression of a Membrane-Anchored Glycoprotein, the Influenza Virus Hemagglutinin, by Dicistronic Replicons Derived from the Poliovirus Genome

Mono- and dicistronic poliovirus replicons were constructed to express the influenza virus hemagglutinin, retaining its signal peptide and transmembrane region. Picornavirus genomes do not normally encode glycoproteins, and only the dicistronic replicon, in which the foreign and poliovirus sequences...

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Detalhes bibliográficos
Main Authors: Vignuzzi, Marco, Gerbaud, Sylvie, van der Werf, Sylvie, Escriou, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136135/
https://ncbi.nlm.nih.gov/pubmed/11967344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.10.5285-5290.2002
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