Development of a Novel Dicistronic Reporter-Selectable Hepatitis C Virus Replicon Suitable for High-Throughput Inhibitor Screening

Hepatitis C virus (HCV) research and drug discovery have been facilitated by the introduction of cell lines with self-replicating subgenomic HCV replicons. Early attempts to carry out robust, high-throughput screens (HTS) using HCV replicons have met with limited success. Specifically, selectable re...

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Autors principals: Hao, Weidong, Herlihy, Koleen J., Zhang, Noelle Jie, Fuhrman, Shella A., Doan, Chau, Patick, Amy K., Duggal, Rohit
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
Matèries:
Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797688/
https://ncbi.nlm.nih.gov/pubmed/17060518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01008-06
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