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Expression of a Membrane-Anchored Glycoprotein, the Influenza Virus Hemagglutinin, by Dicistronic Replicons Derived from the Poliovirus Genome

Mono- and dicistronic poliovirus replicons were constructed to express the influenza virus hemagglutinin, retaining its signal peptide and transmembrane region. Picornavirus genomes do not normally encode glycoproteins, and only the dicistronic replicon, in which the foreign and poliovirus sequences...

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Détails bibliographiques
Auteurs principaux: Vignuzzi, Marco, Gerbaud, Sylvie, van der Werf, Sylvie, Escriou, Nicolas
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC136135/
https://ncbi.nlm.nih.gov/pubmed/11967344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.10.5285-5290.2002
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