Mutations That Confer Resistance to Template-Analog Inhibitors of Human Immunodeficiency Virus (HIV) Type 1 Reverse Transcriptase Lead to Severe Defects in HIV Replication

Eitemau Tebyg

• Potent Inhibition of Human Immunodeficiency Virus Type 1 Replication by Template Analog Reverse Transcriptase Inhibitors Derived by SELEX (Systematic Evolution of Ligands by Exponential Enrichment)
  gan: Joshi, Pheroze, et al.
  Cyhoeddwyd: (2002)
• Hypersusceptibility to Substrate Analogs Conferred by Mutations in Human Immunodeficiency Virus Type 1 Reverse Transcriptase
  gan: Smith, Robert A., et al.
  Cyhoeddwyd: (2006)
• HIV-1 reverse transcriptase mutations that confer decreased in vitro susceptibility to anti-RT DNA aptamer RT1t49 confer cross resistance to other anti-RT aptamers but not to standard RT inhibitors
  gan: Fisher, Timothy S, et al.
  Cyhoeddwyd: (2005)
• Interaction between Human Immunodeficiency Virus Type 1 Reverse Transcriptase and Integrase Proteins
  gan: Hehl, Eric A., et al.
  Cyhoeddwyd: (2004)
• Gln145Met/Leu Changes in Human Immunodeficiency Virus Type 1 Reverse Transcriptase Confer Resistance to Nucleoside and Nonnucleoside Analogs and Impair Virus Replication
  gan: Paolucci, Stefania, et al.
  Cyhoeddwyd: (2004)