4′-Ethynyl Nucleoside Analogs: Potent Inhibitors of Multidrug-Resistant Human Immunodeficiency Virus Variants In Vitro

A series of 4′-ethynyl (4′-E) nucleoside analogs were designed, synthesized, and identified as being active against a wide spectrum of human immunodeficiency viruses (HIV), including a variety of laboratory strains of HIV-1, HIV-2, and primary clinical HIV-1 isolates. Among such analogs examined, 4′...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Kodama, Ei-Ichi, Kohgo, Satoru, Kitano, Kenji, Machida, Haruhiko, Gatanaga, Hiroyuki, Shigeta, Shiro, Matsuoka, Masao, Ohrui, Hiroshi, Mitsuya, Hiroaki
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Antiviral Agents
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90502/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11302824/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.5.1539-1546.2001
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