The M184V Mutation Reduces the Selective Excision of Zidovudine 5′-Monophosphate (AZTMP) by the Reverse Transcriptase of Human Immunodeficiency Virus Type 1

The M184V mutation in human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) causes resistance to lamivudine, but it also increases the sensitivity of the virus to zidovudine (3′-azido-3′-deoxythymidine; AZT). This sensitization to AZT is seen both in the presence and the absence of...

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Bibliografische gegevens

Gepubliceerd in:	J Virol
Hoofdauteurs:	Boyer, Paul L., Sarafianos, Stefan G., Arnold, Edward, Hughes, Stephen H.
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	American Society for Microbiology (ASM) 2002
Onderwerpen:	Vaccines and Antiviral Agents
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136050/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11884549/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.7.3248-3256.2002
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