The M184V Mutation Reduces the Selective Excision of Zidovudine 5′-Monophosphate (AZTMP) by the Reverse Transcriptase of Human Immunodeficiency Virus Type 1

The M184V mutation in human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) causes resistance to lamivudine, but it also increases the sensitivity of the virus to zidovudine (3′-azido-3′-deoxythymidine; AZT). This sensitization to AZT is seen both in the presence and the absence of...

Description complète

Détails bibliographiques

Publié dans:	J Virol
Auteurs principaux:	Boyer, Paul L., Sarafianos, Stefan G., Arnold, Edward, Hughes, Stephen H.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2002
Sujets:	Vaccines and Antiviral Agents
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136050/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11884549/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.7.3248-3256.2002
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!