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Correlation of Molecular Characteristics, Isotype, and In Vitro Functional Activity of Human Antipneumococcal Monoclonal Antibodies

Structure-function correlations of pneumococcal antibodies are important in predicting how changes in the pneumococcus (Pnc)-specific B-cell repertoire will influence humoral immunity against invasive Pnc disease. Using a unique panel of human hybridomas derived from memory B cells after pneumococca...

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Bibliographic Details
Main Authors: Baxendale, H. E., Goldblatt, D.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360365/
https://ncbi.nlm.nih.gov/pubmed/16428749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.2.1025-1031.2006
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