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Monoclonal Antibodies of a Diverse Isotype Induced by an O-Antigen Glycoconjugate Vaccine Mediate In Vitro and In Vivo Killing of African Invasive Nontyphoidal Salmonella

Nontyphoidal Salmonella (NTS), particularly Salmonella enterica serovars Typhimurium and Enteritidis, is responsible for a major global burden of invasive disease with high associated case-fatality rates. We recently reported the development of a candidate O-antigen–CRM(197) glycoconjugate vaccine a...

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發表在:Infect Immun
Main Authors: Goh, Yun Shan, Clare, Simon, Micoli, Francesca, Saul, Allan, Mastroeni, Pietro, MacLennan, Calman A.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534659/
https://ncbi.nlm.nih.gov/pubmed/26169269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00547-15
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