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Ancylostoma caninum MTP-1, an Astacin-Like Metalloprotease Secreted by Infective Hookworm Larvae, Is Involved in Tissue Migration

Infective larvae (L3) of nematodes secrete macromolecules that are critical to infection and establishment of the parasite in the host. The dog hookworm Ancylostoma caninum secretes an astacin-like metalloprotease, Ac-MTP-1, upon activation in vitro with host serum. Recombinant Ac-MTP-1 was expresse...

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Библиографические подробности
Главные авторы: Williamson, Angela L., Lustigman, Sara, Oksov, Yelena, Deumic, Vehid, Plieskatt, Jordan, Mendez, Susana, Zhan, Bin, Bottazzi, Maria Elena, Hotez, Peter J., Loukas, Alex
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2006
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360348/
https://ncbi.nlm.nih.gov/pubmed/16428741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.2.961-967.2006
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