Ancylostoma caninum MTP-1, an Astacin-Like Metalloprotease Secreted by Infective Hookworm Larvae, Is Involved in Tissue Migration

Infective larvae (L3) of nematodes secrete macromolecules that are critical to infection and establishment of the parasite in the host. The dog hookworm Ancylostoma caninum secretes an astacin-like metalloprotease, Ac-MTP-1, upon activation in vitro with host serum. Recombinant Ac-MTP-1 was expresse...

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Detalhes bibliográficos
Main Authors: Williamson, Angela L., Lustigman, Sara, Oksov, Yelena, Deumic, Vehid, Plieskatt, Jordan, Mendez, Susana, Zhan, Bin, Bottazzi, Maria Elena, Hotez, Peter J., Loukas, Alex
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360348/
https://ncbi.nlm.nih.gov/pubmed/16428741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.2.961-967.2006
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