Molecular Cloning, Biochemical Characterization, and Partial Protective Immunity of the Heme-Binding Glutathione S-Transferases from the Human Hookworm Necator americanus

Hookworm glutathione S-transferases (GSTs) are critical for parasite blood feeding and survival and represent potential targets for vaccination. Three cDNAs, each encoding a full-length GST protein from the human hookworm Necator americanus (and designated Na-GST-1, Na-GST-2, and Na-GST-3, respectiv...

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Main Authors: Zhan, Bin, Perally, Samirah, Brophy, Peter M., Xue, Jian, Goud, Gaddam, Liu, Sen, Deumic, Vehid, de Oliveira, Luciana M., Bethony, Jeffrey, Bottazzi, Maria Elena, Jiang, Desheng, Gillespie, Portia, Xiao, Shu-hua, Gupta, Richi, Loukas, Alex, Ranjit, Najju, Lustigman, Sara, Oksov, Yelena, Hotez, Peter
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Fungal and Parasitic Infections
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849424/
https://ncbi.nlm.nih.gov/pubmed/20145100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00848-09
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