Ancylostoma caninum MTP-1, an Astacin-Like Metalloprotease Secreted by Infective Hookworm Larvae, Is Involved in Tissue Migration

Infective larvae (L3) of nematodes secrete macromolecules that are critical to infection and establishment of the parasite in the host. The dog hookworm Ancylostoma caninum secretes an astacin-like metalloprotease, Ac-MTP-1, upon activation in vitro with host serum. Recombinant Ac-MTP-1 was expresse...

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Bibliographische Detailangaben
Hauptverfasser: Williamson, Angela L., Lustigman, Sara, Oksov, Yelena, Deumic, Vehid, Plieskatt, Jordan, Mendez, Susana, Zhan, Bin, Bottazzi, Maria Elena, Hotez, Peter J., Loukas, Alex
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
Schlagworte:
Fungal and Parasitic Infections
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360348/
https://ncbi.nlm.nih.gov/pubmed/16428741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.2.961-967.2006
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