Ancylostoma caninum MTP-1, an Astacin-Like Metalloprotease Secreted by Infective Hookworm Larvae, Is Involved in Tissue Migration

Infective larvae (L3) of nematodes secrete macromolecules that are critical to infection and establishment of the parasite in the host. The dog hookworm Ancylostoma caninum secretes an astacin-like metalloprotease, Ac-MTP-1, upon activation in vitro with host serum. Recombinant Ac-MTP-1 was expresse...

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Main Authors: Williamson, Angela L., Lustigman, Sara, Oksov, Yelena, Deumic, Vehid, Plieskatt, Jordan, Mendez, Susana, Zhan, Bin, Bottazzi, Maria Elena, Hotez, Peter J., Loukas, Alex
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2006
Ábhair:
Fungal and Parasitic Infections
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360348/
https://ncbi.nlm.nih.gov/pubmed/16428741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.2.961-967.2006
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