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Unwind and slow down: checkpoint activation by helicase and polymerase uncoupling
Phosphoinositide 3-kinase related protein kinases (PIKK) including ataxia-telangiectasia mutated (ATM), DNA-dependent protein kinase (DNA-PK), and ATM and Rad3-related (ATR) coordinate cellular responses to DNA damage. DNA-PK and ATM are primarily activated by double-strand breaks. The ATR kinase, i...
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| Hovedforfatter: | |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1360198/ https://ncbi.nlm.nih.gov/pubmed/15879550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1316905 |
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