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CD28(−/−) Mice Show Defects in Cellular and Humoral Immunity but Are Able To Control Infection with Murine Gammaherpesvirus 68

The role of CD28-dependent costimulatory interactions in the development and maintenance of antiviral immune responses was investigated in a mouse model of gammaherpesvirus infection. CD28(−/−) mice could clear a productive infection with murine gammaherpesvirus 68 (MHV-68), although early lung vira...

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Bibliographic Details
Main Authors: Lee, Bong Joo, Reiter, Su Khoh, Anderson, Mandy, Sarawar, Sally R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC136005/
https://ncbi.nlm.nih.gov/pubmed/11861872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.6.3049-3053.2002
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