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Lymphotoxin-α-Deficient Mice Can Clear a Productive Infection with Murine Gammaherpesvirus 68 but Fail To Develop Splenomegaly or Lymphocytosis

Respiratory challenge with murine gammaherpesvirus 68 (MHV-68) leads to an acute productive infection of the lung and a persistent latent infection in B lymphocytes, epithelia, and macrophages. The virus also induces splenomegaly and an increase in the number of activated CD8 T cells in the circulat...

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Detalhes bibliográficos
Main Authors: Lee, Bong Joo, Santee, Sybil, Von Gesjen, Sigrid, Ware, Carl F., Sarawar, Sally R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC111769/
https://ncbi.nlm.nih.gov/pubmed/10684295
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