CD28(−/−) Mice Show Defects in Cellular and Humoral Immunity but Are Able To Control Infection with Murine Gammaherpesvirus 68

The role of CD28-dependent costimulatory interactions in the development and maintenance of antiviral immune responses was investigated in a mouse model of gammaherpesvirus infection. CD28(−/−) mice could clear a productive infection with murine gammaherpesvirus 68 (MHV-68), although early lung vira...

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Vydáno v:	J Virol
Hlavní autoři:	Lee, Bong Joo, Reiter, Su Khoh, Anderson, Mandy, Sarawar, Sally R.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2002
Témata:	Pathogenesis and Immunity
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136005/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11861872/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.6.3049-3053.2002
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