Novel, Chimpanzee Serotype 68-Based Adenoviral Vaccine Carrier for Induction of Antibodies to a Transgene Product

An E1-deletion-containing adenoviral recombinant based on the chimpanzee serotype 68 (AdC68) was developed to express the rabies virus glycoprotein. Mice immunized with this construct (AdC68rab.gp) developed antibodies to rabies virus and remained resistant to challenge with an otherwise lethal dose...

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Hlavní autoři: Xiang, Zhiquan, Gao, Guangping, Reyes-Sandoval, Arturo, Cohen, Christopher J., Li, Yan, Bergelson, Jeffrey M., Wilson, James M., Ertl, Hildegund C. J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2002
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC135983/
https://ncbi.nlm.nih.gov/pubmed/11861833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.6.2667-2675.2002
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