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Novel, Chimpanzee Serotype 68-Based Adenoviral Vaccine Carrier for Induction of Antibodies to a Transgene Product

An E1-deletion-containing adenoviral recombinant based on the chimpanzee serotype 68 (AdC68) was developed to express the rabies virus glycoprotein. Mice immunized with this construct (AdC68rab.gp) developed antibodies to rabies virus and remained resistant to challenge with an otherwise lethal dose...

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Autors principals: Xiang, Zhiquan, Gao, Guangping, Reyes-Sandoval, Arturo, Cohen, Christopher J., Li, Yan, Bergelson, Jeffrey M., Wilson, James M., Ertl, Hildegund C. J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC135983/
https://ncbi.nlm.nih.gov/pubmed/11861833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.6.2667-2675.2002
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