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Herpes Simplex Virus Vectors Elicit Durable Immune Responses in the Presence of Preexisting Host Immunity

Herpes simplex virus (HSV) recombinants are being developed as vaccine vectors for the expression of heterologous antigens. There is concern, however, that preexisting HSV immunity may decrease their effectiveness. We have addressed this issue in an animal model. Immunized mice were inoculated with...

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Detalhes bibliográficos
Main Authors: Brockman, Mark A., Knipe, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136066/
https://ncbi.nlm.nih.gov/pubmed/11907207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.8.3678-3687.2002
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